TY - JOUR
KW - Animals
KW - Disease Models, Animal
KW - Female
KW - Hibernation
KW - Kidney
KW - leprosy
KW - Lung
KW - Male
KW - Mycobacterium leprae
KW - Sciuridae
KW - Skin
KW - Spleen
AU - Galletti G
AU - Cavicchi G
AU - Ussia G
AB - <p>Subcutaneous injections of 10(6) acid-fast bacteria from human lepromatous tissue to hibernating ground squirrels (Citellus tridecemlineatus) is followed by generalized infection of the animals and spontaneous death. The number of mycobacteria is high in the skin of GS during winter and decreases during summer. Animals surviving the first hibernation period invariably die during the second. The number of microorganism in the visceral organs is low at all times. The system of infected hibernating GS is a valuable model for the experimental study of leprosy.</p>
BT - Acta leprologica
C1 - http://www.ncbi.nlm.nih.gov/pubmed/6818816?dopt=Abstract
DA - 1982 Jul-Sep
IS - 88
J2 - Acta Leprol
LA - eng
N2 - <p>Subcutaneous injections of 10(6) acid-fast bacteria from human lepromatous tissue to hibernating ground squirrels (Citellus tridecemlineatus) is followed by generalized infection of the animals and spontaneous death. The number of mycobacteria is high in the skin of GS during winter and decreases during summer. Animals surviving the first hibernation period invariably die during the second. The number of microorganism in the visceral organs is low at all times. The system of infected hibernating GS is a valuable model for the experimental study of leprosy.</p>
PY - 1982
SP - 23
EP - 31
T2 - Acta leprologica
TI - Replication of Mycobacterium leprae in hibernating ground squirrels (Citellus tridecemlineatus).
SN - 0001-5938
ER -