TY - JOUR KW - Cell Migration Inhibition KW - Haptens KW - Humans KW - Lactones KW - leprosy KW - Leukocytes KW - Mycobacterium leprae KW - Tetanus Toxoid AU - Fotedar A AU - Mustafa A S AU - Narang B S AU - Talwar G P AB -
Two acetoacetylated derivatives of Mycobacterium leprae with variable hapten groups and a conjugate with tetanus toxoid were prepared. These were tested as antigens along with unmodified M. leprae in the leucocyte migration inhibition response of leucocytes from clinically, bacteriologically and histopathologically confirmed cases of lepromatous leprosy. LMI response was poor with M. leprae, but was significantly enhanced with acetoacetylated M. leprae.
BT - Clinical and experimental immunology C1 - http://www.ncbi.nlm.nih.gov/pubmed/6751637?dopt=Abstract DA - 1982 Aug IS - 2 J2 - Clin. Exp. Immunol. LA - eng N2 -Two acetoacetylated derivatives of Mycobacterium leprae with variable hapten groups and a conjugate with tetanus toxoid were prepared. These were tested as antigens along with unmodified M. leprae in the leucocyte migration inhibition response of leucocytes from clinically, bacteriologically and histopathologically confirmed cases of lepromatous leprosy. LMI response was poor with M. leprae, but was significantly enhanced with acetoacetylated M. leprae.
PY - 1982 SP - 317 EP - 24 T2 - Clinical and experimental immunology TI - Improved leucocyte migration inhibition response of leucocytes from lepromatous leprosy patients with hapten modified M. leprae. UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1536491/pdf/clinexpimmunol00167-0063.pdf VL - 49 SN - 0009-9104 ER -