TY - JOUR KW - Dapsone KW - Dinitrochlorobenzene KW - Humans KW - Hypersensitivity, Delayed KW - leprosy KW - Macrophage Migration-Inhibitory Factors KW - Molecular Weight KW - Muramidase KW - Prednisone KW - Thalidomide AU - Rea T H AU - Yoshida T AB -

We have found that 26 of 54 (48%) untreated patients with leprosy had serum migration inhibitory activity, and that this was present in tuberculoid, borderline, and lepromatous forms of the disease. Patients with active recreational states; i.e., reversal reactions, Lucio's reaction, or erythema nodosum leprosum, were particularly apt to have this inhibitory activity. The prevalence of inhibitory activity did not vary significantly with treatment, dinitrochlorobenzene responsiveness, tuberculin responsiveness, or serum lysozyme levels.

BT - The Journal of investigative dermatology C1 - http://www.ncbi.nlm.nih.gov/pubmed/6752294?dopt=Abstract DA - 1982 Nov DO - 10.1111/1523-1747.ep12500088 IS - 5 J2 - J. Invest. Dermatol. LA - eng N2 -

We have found that 26 of 54 (48%) untreated patients with leprosy had serum migration inhibitory activity, and that this was present in tuberculoid, borderline, and lepromatous forms of the disease. Patients with active recreational states; i.e., reversal reactions, Lucio's reaction, or erythema nodosum leprosum, were particularly apt to have this inhibitory activity. The prevalence of inhibitory activity did not vary significantly with treatment, dinitrochlorobenzene responsiveness, tuberculin responsiveness, or serum lysozyme levels.

PY - 1982 SP - 336 EP - 9 T2 - The Journal of investigative dermatology TI - Serum macrophage migration inhibition activity in patients with leprosy. VL - 79 SN - 0022-202X ER -