Biopsies of macular hypopigmented lesions, in twenty one untreated cases, representing the whole spectrum of leprosy, revealed a high incidence of disagreement between clinical and histopathological classification. It was not observed in macular tuberculoid and indeterminate cases but was seen in borderline and lepromatous leprosy, with highest incidence in borderline leprosy. This has been explained on the basis of complex nervous system with a mosaic of anatomical and physiological subunits, modulating different types of responses including inflammation, through release of peptides and/or enzymes at the nerve endings in the peripheral tissues including skin.
BT - Leprosy in India C1 - http://www.ncbi.nlm.nih.gov/pubmed/6656203?dopt=Abstract CN - Infolep Library - available DA - 1983 Jul IS - 3 J2 - Lepr India LA - eng N2 -Biopsies of macular hypopigmented lesions, in twenty one untreated cases, representing the whole spectrum of leprosy, revealed a high incidence of disagreement between clinical and histopathological classification. It was not observed in macular tuberculoid and indeterminate cases but was seen in borderline and lepromatous leprosy, with highest incidence in borderline leprosy. This has been explained on the basis of complex nervous system with a mosaic of anatomical and physiological subunits, modulating different types of responses including inflammation, through release of peptides and/or enzymes at the nerve endings in the peripheral tissues including skin.
PY - 1983 SP - 472 EP - 9 T2 - Leprosy in India TI - Variations in clinical and histopathological classification of leprosy--a report and a plausible explanation. VL - 55 SN - 0024-1024 ER -