TY - JOUR
KW - Alanine Transaminase
KW - Alkaline Phosphatase
KW - Aspartate Aminotransferases
KW - Bilirubin
KW - Blood Proteins
KW - Clofazimine
KW - Dapsone
KW - Humans
KW - leprosy
KW - Liver
KW - Liver Function Tests
AU - Bulakh P M
AU - Kowale C N
AU - Ranade S M
AU - Burte N P
AU - Chandorkar A G
AB - <p>Twenty patients with suspected DDS resistance and repeated attacks of lepra reactions were selected for the study. Clofazimine was administered in different doses over a period of 12 months. Elevated levels of transaminases and Alkaline phosphatase prior therapy attained values to near normalcy. Progressive fall in serum Bilirubin and Proteins with normal A/G ratio at the end of therapy was also observed. Clofazimine by its anti-inflammatory and antibacterial action could inhibit the process of liver damage and happened to have minimal deleterious effect on liver by studying the liver function tests.</p>
BT - Leprosy in India
C1 - http://www.ncbi.nlm.nih.gov/pubmed/6668931?dopt=Abstract
CN - Infolep Library - available
DA - 1983 Oct
IS - 4
J2 - Lepr India
LA - eng
N2 - <p>Twenty patients with suspected DDS resistance and repeated attacks of lepra reactions were selected for the study. Clofazimine was administered in different doses over a period of 12 months. Elevated levels of transaminases and Alkaline phosphatase prior therapy attained values to near normalcy. Progressive fall in serum Bilirubin and Proteins with normal A/G ratio at the end of therapy was also observed. Clofazimine by its anti-inflammatory and antibacterial action could inhibit the process of liver damage and happened to have minimal deleterious effect on liver by studying the liver function tests.</p>
PY - 1983
SP - 714
EP - 8
T2 - Leprosy in India
TI - The effect of clofazimine on liver function tests in lepra reaction (ENL).
VL - 55
SN - 0024-1024
ER -