Serum alpha one antitrypsin levels were measured in 50 healthy age and sex matched controls with 45 lepromatous leprosy cases and 5 cases of lepra reaction. It was noted that the mean level in healthy controls was 281.00 mg%, while the mean levels in LL patients was 421.00 mg% and in LR 570.00 mg%. The elevation of Alpha one antitrypsin was statistically significant in LL patients. It is possible that the rise is a reaction to release of proteases and or higher complement activity, which are the results of a high bacillary loading to formation of immune complexes.
BT - Leprosy in India C1 - http://www.ncbi.nlm.nih.gov/pubmed/6603564?dopt=Abstract CN - Infolep Library - available DA - 1983 Jan IS - 1 J2 - Lepr India LA - eng N2 -Serum alpha one antitrypsin levels were measured in 50 healthy age and sex matched controls with 45 lepromatous leprosy cases and 5 cases of lepra reaction. It was noted that the mean level in healthy controls was 281.00 mg%, while the mean levels in LL patients was 421.00 mg% and in LR 570.00 mg%. The elevation of Alpha one antitrypsin was statistically significant in LL patients. It is possible that the rise is a reaction to release of proteases and or higher complement activity, which are the results of a high bacillary loading to formation of immune complexes.
PY - 1983 SP - 91 EP - 4 T2 - Leprosy in India TI - Protease inhibitors activity in lepromatous leprosy and lepra reaction. VL - 55 SN - 0024-1024 ER -