TY - JOUR KW - Adult KW - Aged KW - Antibodies, Antinuclear KW - Antigen-Antibody Complex KW - Humans KW - leprosy KW - Middle Aged KW - Phenotype KW - Radioimmunoassay AU - Furukawa F AU - Sekita K AU - Hamashima Y AU - Ozaki M AU - Imamura S AB -

In 79 patients with leprosy a significant increase of anti-extractable nuclear antigen (ENA) antibodies and circulating immune complexes (CIC) was found. No correlation between CIC and anti-ENA antibodies was demonstrable. Since such a correlation is known from antinuclear antibodies and CIC in patients with systemic lupus erythematosus, it appears likely that anti-ENA antibodies do not play a causative role in CIC-mediated pathogenesis of leprosy.

BT - Archives of dermatological research C1 - http://www.ncbi.nlm.nih.gov/pubmed/6604502?dopt=Abstract DA - 1983 DO - 10.1007/bf00510043 IS - 3 J2 - Arch. Dermatol. Res. LA - eng N2 -

In 79 patients with leprosy a significant increase of anti-extractable nuclear antigen (ENA) antibodies and circulating immune complexes (CIC) was found. No correlation between CIC and anti-ENA antibodies was demonstrable. Since such a correlation is known from antinuclear antibodies and CIC in patients with systemic lupus erythematosus, it appears likely that anti-ENA antibodies do not play a causative role in CIC-mediated pathogenesis of leprosy.

PY - 1983 SP - 144 EP - 6 T2 - Archives of dermatological research TI - Evaluation of circulating immune complexes and antinuclear antibodies in Japanese patients with leprosy. VL - 275 SN - 0340-3696 ER -