TY - JOUR
KW - B-Lymphocytes
KW - Dapsone
KW - Female
KW - Humans
KW - Lepromin
KW - leprosy
KW - Leukocyte Count
KW - Lymphocyte Activation
KW - Male
KW - Phytohemagglutinins
KW - T-Lymphocytes
AU - Kumar B
AU - Ganguly N K
AU - Kaur S
AU - Vaishnavi C
AU - Chakravarti R N
AB - <p>T and B cell counts and their response to PHA and lepromin were studied in 46 patients of polar tuberculoid leprosy (TT), divided into two age and sex matched groups. Twenty five normal healthy controls were similarly investigated. While one group consisted of 26 untreated TT patients, the other included 20 individuals who had taken dapsone, 50 mg daily, for 12 to 14 months. There was significant decrease in the number of T-lymphocytes and their response to PHA and lepromin was lower in the treated, as compared to the untreated patients and normal persons. No significant change was found in the number of B-lymphocytes in any of the groups.</p>
BT - Leprosy in India
C1 - http://www.ncbi.nlm.nih.gov/pubmed/6606732?dopt=Abstract
CN - Infolep Library - available
DA - 1983 Jul
IS - 3
J2 - Lepr India
LA - eng
N2 - <p>T and B cell counts and their response to PHA and lepromin were studied in 46 patients of polar tuberculoid leprosy (TT), divided into two age and sex matched groups. Twenty five normal healthy controls were similarly investigated. While one group consisted of 26 untreated TT patients, the other included 20 individuals who had taken dapsone, 50 mg daily, for 12 to 14 months. There was significant decrease in the number of T-lymphocytes and their response to PHA and lepromin was lower in the treated, as compared to the untreated patients and normal persons. No significant change was found in the number of B-lymphocytes in any of the groups.</p>
PY - 1983
SP - 465
EP - 71
T2 - Leprosy in India
TI - Effect of dapsone (DDS) on T-cells and their response to PHA and lepromin in tuberculoid leprosy patients.
VL - 55
SN - 0024-1024
ER -