TY - JOUR KW - Adolescent KW - Adult KW - Clofazimine KW - Dapsone KW - Dose-Response Relationship, Drug KW - Drug Administration Schedule KW - Drug Resistance KW - Drug Therapy, Combination KW - Female KW - Humans KW - leprosy KW - Male KW - Middle Aged KW - Rifampin AU - Kundu S K AU - Hazra S K AU - Chaudhury S AU - Chatterjee B AB -

Rifampicin, Clofazimine and D.D.S. have been tried in fifteen active untreated lepromatous cases for a period of two years. Compared to dapsone monotherapy remarkable clinical and bacteriological improvement was observed with this combined therapy with attainment of negative BI in ten cases. Use of this combination therapy is thus advocated to achieve noninfectivity in a shorter period and to prevent emergence of dapsone resistance thereby causing the path of leprosy control before it becomes unmanageable due to dapsone resistance.

BT - Indian journal of leprosy C1 - http://www.ncbi.nlm.nih.gov/pubmed/6548246?dopt=Abstract CN - Infolep Library - available DA - 1984 Jan-Mar IS - 1 J2 - Indian J Lepr LA - eng N2 -

Rifampicin, Clofazimine and D.D.S. have been tried in fifteen active untreated lepromatous cases for a period of two years. Compared to dapsone monotherapy remarkable clinical and bacteriological improvement was observed with this combined therapy with attainment of negative BI in ten cases. Use of this combination therapy is thus advocated to achieve noninfectivity in a shorter period and to prevent emergence of dapsone resistance thereby causing the path of leprosy control before it becomes unmanageable due to dapsone resistance.

PY - 1984 SP - 78 EP - 85 T2 - Indian journal of leprosy TI - Evaluation of multidrug therapy with rifampicin, clofazimine and D.D.S. in multibacillary leprosy cases. VL - 56 SN - 0254-9395 ER -