Special complications due to intermittent rifampicin administration have been well documented, specially for the treatment of tuberculosis. Multi-drug therapy recommended for the treatment of leprosy by W.H.O. (1982) advocates the administration of rifampicin at monthly interval and at this level of infrequent administration, complications linked with intermittent therapy are seldom noted. An adult male put on W.H.O. regimen for the treatment of lepromatous leprosy developed acute renal failure at the time of second and third monthly doses of rifampicin therapy, but recovered completely due to prompt treatment.
BT - Indian journal of leprosy C1 - http://www.ncbi.nlm.nih.gov/pubmed/6549453?dopt=Abstract CN - Infolep Library - available DA - 1984 Oct-Dec IS - 4 J2 - Indian J Lepr LA - eng N2 -Special complications due to intermittent rifampicin administration have been well documented, specially for the treatment of tuberculosis. Multi-drug therapy recommended for the treatment of leprosy by W.H.O. (1982) advocates the administration of rifampicin at monthly interval and at this level of infrequent administration, complications linked with intermittent therapy are seldom noted. An adult male put on W.H.O. regimen for the treatment of lepromatous leprosy developed acute renal failure at the time of second and third monthly doses of rifampicin therapy, but recovered completely due to prompt treatment.
PY - 1984 SP - 835 EP - 9 T2 - Indian journal of leprosy TI - Reversible acute renal failure due to monthly administration of rifampicin in a leprosy patient. VL - 56 SN - 0254-9395 ER -