TY - JOUR
KW - Adult
KW - Biomarkers
KW - Female
KW - Humans
KW - leprosy
KW - Male
KW - Middle Aged
KW - Nitric Oxide
KW - Prognosis
KW - Recurrence
KW - Sensitivity and Specificity
KW - Severity of Illness Index
KW - Statistics, Nonparametric
AU - Schön T
AU - Gebre N
AU - Sundqvist T
AU - Habetmariam H S
AU - Engeda T
AU - Britton S
AB - <p>We measured the metabolites of NO [nitrite (NO2-) and nitrate (NO3-)] in urine from Ethiopian patients suffering from leprosy. The urinary level of NO2-/NO3- in a group of healthy Ethiopians was 1020 +/- 471 microM (n = 22). Leprosy patients in reversal reaction had significantly higher levels of NO2-/NO3- (1817 +/- 492 microM, p < 0.001, n = 12) than both the control group and leprosy patients who were not in reversal reaction (1079 +/- 446 microM, n = 12). We conclude that the reversal reaction in leprosy in associated with increased urinary levels of nitric oxide metabolites.</p>
BT - Leprosy review
C1 - http://www.ncbi.nlm.nih.gov/pubmed/10438255?dopt=Abstract
CN - SCHON 1999
DA - 1999 Mar
DO - 10.5935/0305-7518.19990011
IS - 1
J2 - Lepr Rev
LA - eng
N2 - <p>We measured the metabolites of NO [nitrite (NO2-) and nitrate (NO3-)] in urine from Ethiopian patients suffering from leprosy. The urinary level of NO2-/NO3- in a group of healthy Ethiopians was 1020 +/- 471 microM (n = 22). Leprosy patients in reversal reaction had significantly higher levels of NO2-/NO3- (1817 +/- 492 microM, p < 0.001, n = 12) than both the control group and leprosy patients who were not in reversal reaction (1079 +/- 446 microM, n = 12). We conclude that the reversal reaction in leprosy in associated with increased urinary levels of nitric oxide metabolites.</p>
PY - 1999
SP - 52
EP - 5
T2 - Leprosy review
TI - Increased levels of nitric oxide metabolites in urine from leprosy patients in reversal reaction.
UR - http://leprev.ilsl.br/pdfs/1999/v70n1/pdf/v70n1a11.pdf
VL - 70
SN - 0305-7518
ER -