TY - JOUR KW - Adult KW - Clofazimine KW - Dapsone KW - Drug Therapy, Combination KW - Humans KW - leprosy KW - Leukocyte Count KW - Male KW - Plasma Exchange KW - Rifampin KW - T-Lymphocytes AU - Lucht F AU - Rifle G AU - Portier H AU - Chalopin J M AU - Bonhomme J AB -
A 24 year old man admitted to hospital with borderline lepromatous leprosy was treated with rifampicin, dapsone, and clofazimine. After four months he developed a reversal reaction and the diagnosis was modified to borderline tuberculoid leprosy. The dose of clofazimine was raised and prednisolone added to the regimen without any symptomatic response. His condition improved dramatically after five plasma exchanges on five successive days.
BT - British medical journal (Clinical research ed.) C1 - http://www.ncbi.nlm.nih.gov/pubmed/6439359?dopt=Abstract DA - 1984 Dec 15 DO - 10.1136/bmj.289.6459.1647 IS - 6459 J2 - Br Med J (Clin Res Ed) LA - eng N2 -A 24 year old man admitted to hospital with borderline lepromatous leprosy was treated with rifampicin, dapsone, and clofazimine. After four months he developed a reversal reaction and the diagnosis was modified to borderline tuberculoid leprosy. The dose of clofazimine was raised and prednisolone added to the regimen without any symptomatic response. His condition improved dramatically after five plasma exchanges on five successive days.
PY - 1984 SP - 1647 EP - 8 T2 - British medical journal (Clinical research ed.) TI - Successful plasma exchange in type 1 leprosy reversal reaction. VL - 289 SN - 0267-0623 ER -