TY - JOUR
KW - Cell Membrane
KW - Humans
KW - Immune Tolerance
KW - Immunity, Cellular
KW - In Vitro Techniques
KW - leprosy
KW - Macrophages
KW - Mycobacterium leprae
KW - Receptors, Concanavalin A
KW - Receptors, Fc
AU - Salgame P R
AU - Birdi T J
AU - Lad S J
AU - Mahadevan P R
AU - Antia N H
AB - <p>L-Lysate induced macrophage membrane alteration was studied using 3 membrane markers: (i) Fc receptor, (ii) Concanavalin A (Con A) receptor, and (iii) M. leprae adherence to macrophage membrane. The data indicate that L-lysate induces membrane perturbation of normal macrophages. The alteration can be reversed with trypsin and colchicine. Membrane alteration observed may lead to defective macrophage participation in a cell-mediated immune reaction.</p>
BT - Journal of clinical & laboratory immunology
C1 - http://www.ncbi.nlm.nih.gov/pubmed/6384522?dopt=Abstract
DA - 1984 Jul
IS - 3
J2 - J Clin Lab Immunol
LA - eng
N2 - <p>L-Lysate induced macrophage membrane alteration was studied using 3 membrane markers: (i) Fc receptor, (ii) Concanavalin A (Con A) receptor, and (iii) M. leprae adherence to macrophage membrane. The data indicate that L-lysate induces membrane perturbation of normal macrophages. The alteration can be reversed with trypsin and colchicine. Membrane alteration observed may lead to defective macrophage participation in a cell-mediated immune reaction.</p>
PY - 1984
SP - 145
EP - 9
T2 - Journal of clinical & laboratory immunology
TI - Mechanism of immunosuppression in leprosy--macrophage membrane alterations.
VL - 14
SN - 0141-2760
ER -