TY - JOUR KW - Adolescent KW - Adult KW - Bacterial Vaccines KW - Child KW - Erythema Nodosum KW - Granuloma KW - Humans KW - Lepromin KW - leprosy KW - Lymphocytes KW - Male KW - Middle Aged KW - Mycobacterium leprae KW - Skin KW - Vaccination AU - Bhatki W S AU - Chulawala R G AU - BAPAT C V AU - Deo M G AB -

Clinico-pathological features of five cases of lepromatous leprosy exhibiting "reversal" reaction with upgrading of lesions following vaccination with ICRC vaccine have been described. Two patients also developed ENL. Associated with the "reversal" reaction, the patients exhibited lepromin conversion. No evidence of fresh nerve lesions was observed in any patient. Besides lepromin conversion, occurrence of "reversal" reaction is yet another evidence of immunogenicity of the ICRC vaccine.

BT - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association C1 - http://www.ncbi.nlm.nih.gov/pubmed/6368413?dopt=Abstract DA - 1983 Dec IS - 4 J2 - Int. J. Lepr. Other Mycobact. Dis. LA - eng N2 -

Clinico-pathological features of five cases of lepromatous leprosy exhibiting "reversal" reaction with upgrading of lesions following vaccination with ICRC vaccine have been described. Two patients also developed ENL. Associated with the "reversal" reaction, the patients exhibited lepromin conversion. No evidence of fresh nerve lesions was observed in any patient. Besides lepromin conversion, occurrence of "reversal" reaction is yet another evidence of immunogenicity of the ICRC vaccine.

PY - 1983 SP - 466 EP - 72 T2 - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association TI - Reversal reaction in lepromatous patients induced by a vaccine containing killed ICRC bacilli--a report of five cases. UR - http://ila.ilsl.br/pdfs/v51n4a02.pdf VL - 51 SN - 0148-916X ER -