TY - JOUR
KW - Histocompatibility Antigens Class II
KW - HLA-DR Antigens
KW - Humans
KW - Immunity, Cellular
KW - leprosy
KW - Levamisole
KW - Lymphocyte Cooperation
KW - Macrophage Activation
KW - Macrophages
KW - Mycobacterium leprae
KW - Receptors, Fc
KW - Rosette Formation
AU - Birdi T J
AU - Mistry N F
AU - Mahadevan P R
AU - Antia N H
AB - <p>Our previous studies have demonstrated a defective macrophage response to M. leprae in lepromatous leprosy patients. In the present study we report the restoration of Fc receptor and HLA-DR antigen expression as well as antigen specific macrophage-lymphocyte interaction on treatment with levamisole in vitro. These results indicate that levamisole activates the macrophages which in turn results in an improved cell mediated immune response in lepromatous leprosy. This may also be applicable in other disease situations.</p>
BT - Journal of clinical & laboratory immunology
C1 - http://www.ncbi.nlm.nih.gov/pubmed/6374154?dopt=Abstract
DA - 1984 Feb
IS - 2
J2 - J Clin Lab Immunol
LA - eng
N2 - <p>Our previous studies have demonstrated a defective macrophage response to M. leprae in lepromatous leprosy patients. In the present study we report the restoration of Fc receptor and HLA-DR antigen expression as well as antigen specific macrophage-lymphocyte interaction on treatment with levamisole in vitro. These results indicate that levamisole activates the macrophages which in turn results in an improved cell mediated immune response in lepromatous leprosy. This may also be applicable in other disease situations.</p>
PY - 1984
SP - 93
EP - 6
T2 - Journal of clinical & laboratory immunology
TI - In vitro studies on the effect of levamisole in lepromatous leprosy.
VL - 13
SN - 0141-2760
ER -