TY - JOUR
KW - Animals
KW - Armadillos
KW - Cebus
KW - Cercopithecus aethiops
KW - Freeze Etching
KW - leprosy
KW - Liver
KW - Macaca mulatta
KW - Macrophages
KW - Monkey Diseases
KW - Mycobacterium leprae
AU - Fukunishi Y
AU - Meyers W M
AU - Binford C H
AU - Walsh G P
AU - Johnson F B
AU - Gerone P J
AU - Wolf R H
AU - Gormus B J
AU - Martin L N
AB - <p>Ultrastructural features of the leproma of a) a naturally infected mangabey monkey, and lepromas and liver of b) a passage mangabey monkey, c) a rhesus monkey, d) an African green monkey, and e) a nine-banded armadillo inoculated with leprosy bacilli isolated from the leproma of a naturally infected mangabey monkey were studied by the freeze-etching technique. The size, shape, and ultrastructural features of leprosy bacilli in the phagolysosomes of macrophages in all of these samples were essentially the same as those in humans, nude mice, and armadillos inoculated with human Mycobacterium leprae. Distinct accumulations of small spherical droplets were observed around leprosy bacilli inside lepra cells of all the samples but were scarce in the specimen from the green monkey. The bacilli in all samples were long and slender, and had band structures on the smooth cell wall surfaces. The bacilli were indistinguishable from M. leprae.</p>
BT - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association
C1 - http://www.ncbi.nlm.nih.gov/pubmed/6373629?dopt=Abstract
DA - 1984 Jun
IS - 2
J2 - Int. J. Lepr. Other Mycobact. Dis.
LA - eng
N2 - <p>Ultrastructural features of the leproma of a) a naturally infected mangabey monkey, and lepromas and liver of b) a passage mangabey monkey, c) a rhesus monkey, d) an African green monkey, and e) a nine-banded armadillo inoculated with leprosy bacilli isolated from the leproma of a naturally infected mangabey monkey were studied by the freeze-etching technique. The size, shape, and ultrastructural features of leprosy bacilli in the phagolysosomes of macrophages in all of these samples were essentially the same as those in humans, nude mice, and armadillos inoculated with human Mycobacterium leprae. Distinct accumulations of small spherical droplets were observed around leprosy bacilli inside lepra cells of all the samples but were scarce in the specimen from the green monkey. The bacilli in all samples were long and slender, and had band structures on the smooth cell wall surfaces. The bacilli were indistinguishable from M. leprae.</p>
PY - 1984
SP - 203
EP - 7
T2 - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association
TI - Electron microscopic study of leprosy in a mangabey monkey (natural infection).
VL - 52
SN - 0148-916X
ER -