TY - JOUR
KW - Animals
KW - Endothelium
KW - Granuloma
KW - Kupffer Cells
KW - leprosy
KW - Liver
KW - Mice
KW - Mice, Nude
KW - Microscopy, Electron
KW - Mycobacterium leprae
KW - Phagocytosis
KW - Vacuoles
AU - Job C K
AU - Chehl S
AU - Hastings R C
AU - Ruby J R
AB - <p>Liver tissue from a nude mouse infected with Mycobacterium leprae for 18 months was examined using light and electron microscopes. Numerous microgranulomas composed of macrophages were present throughout the liver. M. leprae in large numbers were present in Kupffer cells, macrophages, endothelial cells, and liver parenchymal cells. The study shows that the lower temperature of about 31 degrees C optimal for the growth of M. leprae is relative rather than absolute, and that M. leprae can invade even liver cells.</p>
BT - The American journal of tropical medicine and hygiene
C1 - http://www.ncbi.nlm.nih.gov/pubmed/6353954?dopt=Abstract
DA - 1983 Sep
DO - 10.4269/ajtmh.1983.32.1088
IS - 5
J2 - Am. J. Trop. Med. Hyg.
LA - eng
N2 - <p>Liver tissue from a nude mouse infected with Mycobacterium leprae for 18 months was examined using light and electron microscopes. Numerous microgranulomas composed of macrophages were present throughout the liver. M. leprae in large numbers were present in Kupffer cells, macrophages, endothelial cells, and liver parenchymal cells. The study shows that the lower temperature of about 31 degrees C optimal for the growth of M. leprae is relative rather than absolute, and that M. leprae can invade even liver cells.</p>
PY - 1983
SP - 1088
EP - 95
T2 - The American journal of tropical medicine and hygiene
TI - Invasion of liver parenchymal cells by Mycobacterium leprae in an experimentally infected nude mouse. An electron microscopic study.
VL - 32
SN - 0002-9637
ER -