TY - JOUR
KW - Enzyme-Linked Immunosorbent Assay
KW - Glycolipids
KW - Humans
KW - leprosy
KW - Mycobacterium leprae
KW - Serologic Tests
AU - Young D B
AU - Buchanan T M
AB - <p>A phenolic glycolipid from Mycobacterium leprae was purified and used as antigen in an enzyme-linked immunosorbent assay. Antibodies directed against the lipid were seen in serums from leprosy patients but not in serums from uninfected controls or patients infected with other mycobacteria, including Mycobacterium tuberculosis. The antibody response distinguished between the Mycobacterium leprae lipid and the structurally related phenolic glycolipid from Mycobacterium kansasii. This assay has considerable potential as a specific serodiagnostic test for leprosy infection.</p>
BT - Science (New York, N.Y.)
C1 - http://www.ncbi.nlm.nih.gov/pubmed/6348948?dopt=Abstract
DA - 1983 Sep 09
DO - 10.1126/science.6348948
IS - 4615
J2 - Science
LA - eng
N2 - <p>A phenolic glycolipid from Mycobacterium leprae was purified and used as antigen in an enzyme-linked immunosorbent assay. Antibodies directed against the lipid were seen in serums from leprosy patients but not in serums from uninfected controls or patients infected with other mycobacteria, including Mycobacterium tuberculosis. The antibody response distinguished between the Mycobacterium leprae lipid and the structurally related phenolic glycolipid from Mycobacterium kansasii. This assay has considerable potential as a specific serodiagnostic test for leprosy infection.</p>
PY - 1983
SP - 1057
EP - 9
T2 - Science (New York, N.Y.)
TI - A serological test for leprosy with a glycolipid specific for Mycobacterium leprae.
VL - 221
SN - 0036-8075
ER -