We report on the cellular composition of the cutaneous lesions of 38 leprosy patients prior to and after 12-18 months of chemotherapy. All of the patients with tuberculoid (TT) disease had OKT4/OKT8 ratios that exceeded 1.0. In the indeterminate patients, the ratio varied depending upon the immune status of the individual. A low ratio of OKT4/OKT8 cells (0.25) was found in the LL patients as previously reported. The low ratio of OKT4/OKT8 in the lesions of lepromatous patients did not undergo significant changes after treatment in spite of a marked reduction in the number of intracellular bacilli.
BT - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association C1 - http://www.ncbi.nlm.nih.gov/pubmed/6336043?dopt=Abstract DA - 1984 Dec IS - 4 J2 - Int. J. Lepr. Other Mycobact. Dis. LA - eng N2 -We report on the cellular composition of the cutaneous lesions of 38 leprosy patients prior to and after 12-18 months of chemotherapy. All of the patients with tuberculoid (TT) disease had OKT4/OKT8 ratios that exceeded 1.0. In the indeterminate patients, the ratio varied depending upon the immune status of the individual. A low ratio of OKT4/OKT8 cells (0.25) was found in the LL patients as previously reported. The low ratio of OKT4/OKT8 in the lesions of lepromatous patients did not undergo significant changes after treatment in spite of a marked reduction in the number of intracellular bacilli.
PY - 1984 SP - 496 EP - 500 T2 - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association TI - Effect of treatment on the cellular composition of cutaneous lesions in leprosy patients. VL - 52 SN - 0148-916X ER -