TY - JOUR
KW - Blood Proteins
KW - Humans
KW - Immunoglobulin A
KW - Immunoglobulin M
KW - Immunoglobulins
KW - leprosy
AU - Gupta S C
AU - Sinha S N
AU - Sharma D
AU - Bajaj A K
AU - Bisht D
AU - Mehrotra T N
AU - Gupta R M
AB - <p>Serum proteins and immunoglobulins were studied in patients suffering from various types of leprosy. A significant increase in total protein and decrease in albumin was found in all types of leprosy except borderline-tuberculoid. Gamma globulin was found to be increased in all types. An increase of alpha-2-globulin in lepromatous, a decrease of beta globulin in borderline-lepromatous, and a decrease of alpha-2 and increase of beta globulin in borderline-tuberculoid were observed. These changes do not seem to be of diagnostic importance. A statistically significant increase of IgG in borderline-lepromatous and lepromatous, IgM in all types of leprosy and IgA only in lepromatous was found. The increase of different immunoglobulins in leprosy, especially the lepromatous type, suggests a humoral response which was found to be directly proportional to the severity of the lesion.</p>
BT - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association
C1 - http://www.ncbi.nlm.nih.gov/pubmed/565758?dopt=Abstract
DA - 1978 Jan-Mar
IS - 1
J2 - Int. J. Lepr. Other Mycobact. Dis.
LA - eng
N2 - <p>Serum proteins and immunoglobulins were studied in patients suffering from various types of leprosy. A significant increase in total protein and decrease in albumin was found in all types of leprosy except borderline-tuberculoid. Gamma globulin was found to be increased in all types. An increase of alpha-2-globulin in lepromatous, a decrease of beta globulin in borderline-lepromatous, and a decrease of alpha-2 and increase of beta globulin in borderline-tuberculoid were observed. These changes do not seem to be of diagnostic importance. A statistically significant increase of IgG in borderline-lepromatous and lepromatous, IgM in all types of leprosy and IgA only in lepromatous was found. The increase of different immunoglobulins in leprosy, especially the lepromatous type, suggests a humoral response which was found to be directly proportional to the severity of the lesion.</p>
PY - 1978
SP - 9
EP - 13
T2 - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association
TI - Serum proteins and immunoglobulins in leprosy.
VL - 46
SN - 0148-916X
ER -