TY - JOUR KW - Aged KW - Aged, 80 and over KW - Animals KW - Brazil KW - Dapsone KW - Drug Resistance, Microbial KW - Humans KW - Leprosy, Borderline KW - Male KW - Mice KW - Mice, Inbred BALB C KW - Mycobacterium leprae AU - Gallo M E AU - Damasco M H AU - Alburquerque E C AU - Silva T C AU - Almeida S M AB -

Report on a case of dapsone resistance in a BL patient with clinical diagnosis and laboratory confirmation. The resistance appeared after 17 years of dapsone treatment, and the laboratory tests revealed total resistance to all the tested dapsone concentrations. The case reported occurred in the city of Rio de Janeiro (Brazil) which presents a leprosy prevalence of 1.79/1,000.

BT - Medicina cutanea ibero-latino-americana C1 - http://www.ncbi.nlm.nih.gov/pubmed/2666794?dopt=Abstract DA - 1989 IS - 2 J2 - Med Cutan Ibero Lat Am LA - por N2 -

Report on a case of dapsone resistance in a BL patient with clinical diagnosis and laboratory confirmation. The resistance appeared after 17 years of dapsone treatment, and the laboratory tests revealed total resistance to all the tested dapsone concentrations. The case reported occurred in the city of Rio de Janeiro (Brazil) which presents a leprosy prevalence of 1.79/1,000.

PY - 1989 SP - 103 EP - 4 T2 - Medicina cutanea ibero-latino-americana TI - [Secondary sulfone resistance--presentation of a case of leprosy-Oswaldo Cruz Foundation, Rio de Janeiro-Brazil]. VL - 17 SN - 0210-5187 ER -