TY - JOUR KW - Adolescent KW - Adult KW - Child KW - Child, Preschool KW - Female KW - Humans KW - Infant KW - Lepromin KW - leprosy KW - Male KW - Middle Aged AU - Kundu S K AU - Ghosh S AU - Hazra S K AU - Chaudhury S AB -

A group of 27 families consisting of 176 individuals had been investigated for the lepromin sensitivity (with Dharmendra antigen). The families were arranged under group A (9 families) in whom either of the parents or both were suffering from Lepromatous type of leprosy, group B numbering 4 families, of whom either of the parents or both were suffering from non-lepromatous type of leprosy and group C comprising 14 families where none of the parents was suffering from leprosy but some of the each family had the disease in their siblings. The present study points towards the possible genetic influence on lepromin sensitivity but at times may be influenced by the environmental factors. However the study does not permit to reach any valid conclusions; further elaborate investigations alone could prove the useful role of genetic influence in the propagation of lepromin sensitivity to the subsequent sibs.

BT - Leprosy in India C1 - http://www.ncbi.nlm.nih.gov/pubmed/522440?dopt=Abstract CN - Infolep Library - available DA - 1979 Oct IS - 4 J2 - Lepr India LA - eng N2 -

A group of 27 families consisting of 176 individuals had been investigated for the lepromin sensitivity (with Dharmendra antigen). The families were arranged under group A (9 families) in whom either of the parents or both were suffering from Lepromatous type of leprosy, group B numbering 4 families, of whom either of the parents or both were suffering from non-lepromatous type of leprosy and group C comprising 14 families where none of the parents was suffering from leprosy but some of the each family had the disease in their siblings. The present study points towards the possible genetic influence on lepromin sensitivity but at times may be influenced by the environmental factors. However the study does not permit to reach any valid conclusions; further elaborate investigations alone could prove the useful role of genetic influence in the propagation of lepromin sensitivity to the subsequent sibs.

PY - 1979 SP - 465 EP - 74 T2 - Leprosy in India TI - Nature and familial character of lepromin sensitivity in 27 families and their siblings. VL - 51 SN - 0024-1024 ER -