A 42-year-old man with uveitis and a widespread cutaneous eruption, histopathologically characterized by dermal granulomatous infiltrates with perineurial invasion, was incorrectly diagnosed and treated as having borderline leprosy. Further studies demonstrated secondary syphilis and human immunodeficiency virus (HIV) infection. Standard penicillin therapy resolved his cutaneous and ocular lesions. Reports on clinical and pathological findings of active syphilis in HIV infected patients are scarce but this case and isolated previous case reports suggest that granulomatous infiltrates might be a common feature in secondary syphilis with short evolution in HIV infected patients.
BT - Journal of cutaneous pathology C1 - http://www.ncbi.nlm.nih.gov/pubmed/10189246?dopt=Abstract DA - 1999 Jan DO - 10.1111/j.1600-0560.1999.tb01791.x IS - 1 J2 - J. Cutan. Pathol. LA - eng N2 -A 42-year-old man with uveitis and a widespread cutaneous eruption, histopathologically characterized by dermal granulomatous infiltrates with perineurial invasion, was incorrectly diagnosed and treated as having borderline leprosy. Further studies demonstrated secondary syphilis and human immunodeficiency virus (HIV) infection. Standard penicillin therapy resolved his cutaneous and ocular lesions. Reports on clinical and pathological findings of active syphilis in HIV infected patients are scarce but this case and isolated previous case reports suggest that granulomatous infiltrates might be a common feature in secondary syphilis with short evolution in HIV infected patients.
PY - 1999 SP - 51 EP - 4 T2 - Journal of cutaneous pathology TI - Syphilis in an HIV infected patient misdiagnosed as leprosy. VL - 26 SN - 0303-6987 ER -