In the course fo evaluating the effect of different drugs on the morphology of Mycobacterium leprae (Edwards, Draper & Draper, 1972) and on the phagocytic cells containing these organisms (Edwards, 1973), an unusual feature was observed in the dermal connective tissue of skin biopsies obtained from some of the patients. Variable amounts of an extracellular, cross-striated osmiophilic material were present in the dermis. The purpose of this communication is to describe the banded substance observed in the extracellular space of the lepromatous skin and to compare it briefly with similar substances and structures reported to occur elsewhere.
BT - The British journal of dermatology C1 - http://www.ncbi.nlm.nih.gov/pubmed/51648?dopt=Abstract DA - 1975 Aug DO - 10.1111/j.1365-2133.1975.tb06737.x IS - 2 J2 - Br. J. Dermatol. LA - eng N2 -In the course fo evaluating the effect of different drugs on the morphology of Mycobacterium leprae (Edwards, Draper & Draper, 1972) and on the phagocytic cells containing these organisms (Edwards, 1973), an unusual feature was observed in the dermal connective tissue of skin biopsies obtained from some of the patients. Variable amounts of an extracellular, cross-striated osmiophilic material were present in the dermis. The purpose of this communication is to describe the banded substance observed in the extracellular space of the lepromatous skin and to compare it briefly with similar substances and structures reported to occur elsewhere.
PY - 1975 SP - 175 EP - 82 T2 - The British journal of dermatology TI - Long-spacing collagen in skin biopsies from patients with lepromatous leprosy. VL - 93 SN - 0007-0963 ER -