TY - JOUR
KW - Acedapsone
KW - Adult
KW - Dapsone
KW - Delayed-Action Preparations
KW - Female
KW - Humans
KW - Injections, Intramuscular
KW - leprosy
KW - Male
KW - Middle Aged
AU - Anand L C
AU - Rathore B S
AB - <p>35 cases of lepromatous leprosy were studied to evaluate the effective blood level and long depot action of acedapsone (DADDS). It was revealed that serum level of this drug is maintained well above the minimum inhibitory concentration upto 60 days following single intramuscular injection. No significant untoward effects of the drug were encountered except one case of Erythema Nodosum Leprosum and six patients with mild reactional symptoms in the form of fever and arthralgia.</p>
BT - Leprosy in India
C1 - http://www.ncbi.nlm.nih.gov/pubmed/513651?dopt=Abstract
CN - Infolep Library - available
DA - 1979 Jul
IS - 3
J2 - Lepr India
LA - eng
N2 - <p>35 cases of lepromatous leprosy were studied to evaluate the effective blood level and long depot action of acedapsone (DADDS). It was revealed that serum level of this drug is maintained well above the minimum inhibitory concentration upto 60 days following single intramuscular injection. No significant untoward effects of the drug were encountered except one case of Erythema Nodosum Leprosum and six patients with mild reactional symptoms in the form of fever and arthralgia.</p>
PY - 1979
SP - 358
EP - 62
T2 - Leprosy in India
TI - Activity and effective serum level of repository sulphones (DADDS) in lepromatous leprosy.
VL - 51
SN - 0024-1024
ER -