TY - JOUR
KW - Adolescent
KW - Adult
KW - Aged
KW - Biopsy
KW - Endoscopy
KW - Ethmoid Sinus
KW - Female
KW - Humans
KW - leprosy
KW - Leprosy, Borderline
KW - Leprosy, lepromatous
KW - Male
KW - Middle Aged
KW - Prospective Studies
KW - Tomography, X-Ray Computed
AU - Srinivasan S
AU - Nehru V I
AU - Mann S B
AU - Sharma V K
AU - Bapuraj J R
AU - Das A
AB - <p>The nasal mucosal involvement in lepromatous leprosy is well recognized. Currently interest has centred around the involvement of paranasal sinuses in leprosy. They act as a reservoir and constant source of reinfection to the nasal mucosa. In the present prospective study 25 untreated patients with multi-bacillary leprosy were included. Clinical examination, computed tomography (CT) scan of paranasal sinuses, ethmoid sinus endoscopy and biopsy were carried out in all patients, to investigate the involvement of the paranasal sinuses in leprosy. Ethmoid sinus involvement was noted in 20 patients on CT scan. Bilateral involvement was more common (65 per cent). Anterior ethmoids were more commonly affected (65 per cent). On ethmoid sinus endoscopy abnormal mucosa was noted in 17 patients (68 per cent). Ethmoid sinus biopsy was confirmative in 16 patients (64 per cent). Statistically significant correlation was found between CT findings, sinus endoscopy and sinus biopsy findings.</p>
BT - The Journal of laryngology and otology
C1 - http://www.ncbi.nlm.nih.gov/pubmed/10197140?dopt=Abstract
DA - 1998 Nov
DO - 10.1017/s0022215100142410
IS - 11
J2 - J Laryngol Otol
LA - eng
N2 - <p>The nasal mucosal involvement in lepromatous leprosy is well recognized. Currently interest has centred around the involvement of paranasal sinuses in leprosy. They act as a reservoir and constant source of reinfection to the nasal mucosa. In the present prospective study 25 untreated patients with multi-bacillary leprosy were included. Clinical examination, computed tomography (CT) scan of paranasal sinuses, ethmoid sinus endoscopy and biopsy were carried out in all patients, to investigate the involvement of the paranasal sinuses in leprosy. Ethmoid sinus involvement was noted in 20 patients on CT scan. Bilateral involvement was more common (65 per cent). Anterior ethmoids were more commonly affected (65 per cent). On ethmoid sinus endoscopy abnormal mucosa was noted in 17 patients (68 per cent). Ethmoid sinus biopsy was confirmative in 16 patients (64 per cent). Statistically significant correlation was found between CT findings, sinus endoscopy and sinus biopsy findings.</p>
PY - 1998
SP - 1038
EP - 41
T2 - The Journal of laryngology and otology
TI - Study of ethmoid sinus involvement in multibacillary leprosy.
VL - 112
SN - 0022-2151
ER -