TY - JOUR KW - Adult KW - Female KW - Humans KW - leprosy KW - Male KW - Middle Aged KW - Mycobacterium leprae KW - Neural Conduction KW - Neurofibromatosis 1 KW - Peripheral Nervous System Neoplasms KW - Schwann Cells KW - Skin AU - Swift T R AB -

Two patients with neurofibromatosis and leprosy are reported. Both had active lepromatous leprosy and generalized neurofibromata. The bacilli appear in huge numbers within the cytoplasm of the cells making up the neurofibromata, which become distended and resemble lepra cells. Since these cells are believed to derive from Schwann cells, the findings in these patients support the idea that leprosy affects nerves initially by proliferating in Schwann cells and producing changes within them.

BT - Journal of neurology, neurosurgery, and psychiatry C1 - http://www.ncbi.nlm.nih.gov/pubmed/5003511?dopt=Abstract DA - 1971 Dec DO - 10.1136/jnnp.34.6.743 IS - 6 J2 - J. Neurol. Neurosurg. Psychiatry LA - eng N2 -

Two patients with neurofibromatosis and leprosy are reported. Both had active lepromatous leprosy and generalized neurofibromata. The bacilli appear in huge numbers within the cytoplasm of the cells making up the neurofibromata, which become distended and resemble lepra cells. Since these cells are believed to derive from Schwann cells, the findings in these patients support the idea that leprosy affects nerves initially by proliferating in Schwann cells and producing changes within them.

PY - 1971 SP - 743 EP - 9 T2 - Journal of neurology, neurosurgery, and psychiatry TI - Neurofibromatosis and leprosy. VL - 34 SN - 0022-3050 ER -