TY - JOUR KW - Adult KW - Anti-Inflammatory Agents KW - Body Weight KW - Clinical Trials as Topic KW - Costs and Cost Analysis KW - Dapsone KW - Drug Resistance, Microbial KW - Erythema Nodosum KW - Humans KW - Infant, Newborn KW - leprosy KW - Phenazines KW - Physical Examination AU - Karat A B AU - Jeevaratnam A AU - Karat S AU - Rao P S AB -

A comparison of clofazimine and dapsone in the management of untreated lepromatous leprosy showed no significant differences between the two drugs in terms of morphological and bacterial indices. The incidence of erythema nodosum leprosum was similar in the two groups. Since dapsone is cheaper than clofazimine it remains the drug of choice for the routine management of untreated lepromatous leprosy.

BT - British medical journal C1 - http://www.ncbi.nlm.nih.gov/pubmed/4942741?dopt=Abstract DA - 1971 Nov 27 DO - 10.1136/bmj.4.5786.514 IS - 5786 J2 - Br Med J LA - eng N2 -

A comparison of clofazimine and dapsone in the management of untreated lepromatous leprosy showed no significant differences between the two drugs in terms of morphological and bacterial indices. The incidence of erythema nodosum leprosum was similar in the two groups. Since dapsone is cheaper than clofazimine it remains the drug of choice for the routine management of untreated lepromatous leprosy.

PY - 1971 SP - 514 EP - 6 T2 - British medical journal TI - Controlled clinical trial of clofazimine in untreated lepromatous leprosy. UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1799776/pdf/brmedj02677-0020.pdf VL - 4 SN - 0007-1447 ER -