TY - JOUR
KW - Animals
KW - Disease Models, Animal
KW - Humans
KW - leprosy
KW - Mice
KW - Mycobacterium leprae
KW - Time Factors
KW - Xenarthra
AU - Storrs E E
AU - Walsh G P
AU - Burchfield H P
AU - Binford C H
AB - <p>Eight of twenty armadillos (Dasypus novemcinctus L.) developed severe lepromatous leprosy 3 to 3.5 years after inoculation with viable Mycobacterium leprae. A total of 988 grams of lepromas containing an estimated 15 to 20 grams of leprosy bacilli has been harvested from these animals. The large amounts of material now available will permit in-depth studies of the biochemistry and metabolism of the leprosy bacillus, and the animal model should make possible definitive studies on the immunology, chemotherapy, and epidemiology of the disease.</p>
BT - Science (New York, N.Y.)
C1 - http://www.ncbi.nlm.nih.gov/pubmed/4589901?dopt=Abstract
DA - 1974 Mar 01
DO - 10.1126/science.183.4127.851
IS - 4127
J2 - Science
LA - eng
N2 - <p>Eight of twenty armadillos (Dasypus novemcinctus L.) developed severe lepromatous leprosy 3 to 3.5 years after inoculation with viable Mycobacterium leprae. A total of 988 grams of lepromas containing an estimated 15 to 20 grams of leprosy bacilli has been harvested from these animals. The large amounts of material now available will permit in-depth studies of the biochemistry and metabolism of the leprosy bacillus, and the animal model should make possible definitive studies on the immunology, chemotherapy, and epidemiology of the disease.</p>
PY - 1974
SP - 851
EP - 2
T2 - Science (New York, N.Y.)
TI - Leprosy in the armadillo: new model for biomedical research.
VL - 183
SN - 0036-8075
ER -