TY - JOUR KW - Adult KW - Dapsone KW - Female KW - Humans KW - leprosy KW - Male KW - Rifampin AU - Balakrishnan S AU - Sheshadri P S AB -

The plasma half-lives and urinary excretion levels of DDS were compared before and during concurrent administration of Rifampicin in 23 cases of active lepromatous leprosy. The plasma half-life of DDS was found to be slightly less during Rifampicin administration. The urinary excretion of DDS was found to be consistently enhanced in all the cases, particularly duotal duration of Rifampicin therapy. The findings are discussed.

BT - Leprosy in India C1 - http://www.ncbi.nlm.nih.gov/pubmed/449285?dopt=Abstract CN - Infolep Library - available DA - 1979 Jan IS - 1 J2 - Lepr India LA - eng N2 -

The plasma half-lives and urinary excretion levels of DDS were compared before and during concurrent administration of Rifampicin in 23 cases of active lepromatous leprosy. The plasma half-life of DDS was found to be slightly less during Rifampicin administration. The urinary excretion of DDS was found to be consistently enhanced in all the cases, particularly duotal duration of Rifampicin therapy. The findings are discussed.

PY - 1979 SP - 54 EP - 9 T2 - Leprosy in India TI - Influence of rifampicin on D.D.S. excretion in urine. VL - 51 SN - 0024-1024 ER -