TY - JOUR
KW - Adrenocorticotropic Hormone
KW - Erythema Nodosum
KW - Histological Techniques
KW - Humans
KW - leprosy
KW - Lymph Nodes
KW - Lymphadenitis
KW - Mycobacterium leprae
KW - Necrosis
KW - Prednisolone
AU - Karat A B
AU - Karat S
AU - Job C K
AU - Sudarsanam D
AB - <p>Histological examination of lymph-node biopsy specimens in 12 patients with erythema nodosum leprosum showed almost complete replacement of the node by lepromatous granuloma, together with considerable polymorph infiltration. Ziehl-Neelsen staining demonstrated numerous Mycobacterium leprae present in the nodes. The majority of these patients were very ill, and responded to prednisolone or corticotrophin.It is suggested that the histological appearances may represent an intensive inflammatory response in the lymph nodes followed by avascular aseptic necrosis.</p>
BT - British medical journal
C1 - http://www.ncbi.nlm.nih.gov/pubmed/4300767?dopt=Abstract
DA - 1968 Oct 26
DO - 10.1136/bmj.4.5625.223
IS - 5625
J2 - Br Med J
LA - eng
N2 - <p>Histological examination of lymph-node biopsy specimens in 12 patients with erythema nodosum leprosum showed almost complete replacement of the node by lepromatous granuloma, together with considerable polymorph infiltration. Ziehl-Neelsen staining demonstrated numerous Mycobacterium leprae present in the nodes. The majority of these patients were very ill, and responded to prednisolone or corticotrophin.It is suggested that the histological appearances may represent an intensive inflammatory response in the lymph nodes followed by avascular aseptic necrosis.</p>
PY - 1968
SP - 223
EP - 4
T2 - British medical journal
TI - Acute necrotizing lepromatous lymphadenitis: an erythema-nodosum-leprosum-like reaction in lymph nodes.
VL - 4
SN - 0007-1447
ER -