TY - JOUR
KW - Humans
KW - Immunoglobulin A
KW - Immunoglobulin D
KW - Immunoglobulin Fab Fragments
KW - Immunoglobulin Fc Fragments
KW - Immunoglobulin G
KW - Immunoglobulin kappa-Chains
KW - Immunoglobulin M
KW - Immunoglobulins
KW - leprosy
AU - Kwapinski G
AU - Kwapinski E
AU - DE ALMEIDA J O
AB - <p>A new, abnormal immunoglobulin designated IgK has been discovered in leprous Rubino-negative sera. The IgK having a negative net charge and its own antigenic specificity appears to be partly related to the Fc fragment of IgA and to Fab fragments of known immunoglobulins, but its net charge is negative at pH 8.8. Its molecule seems to possess kappa but not lambda light polypeptide chains. Implications of this discovery are discussed.</p>
BT - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association
C1 - http://www.ncbi.nlm.nih.gov/pubmed/406209?dopt=Abstract
DA - 1977 Jan-Mar
IS - 1
J2 - Int. J. Lepr. Other Mycobact. Dis.
LA - eng
N2 - <p>A new, abnormal immunoglobulin designated IgK has been discovered in leprous Rubino-negative sera. The IgK having a negative net charge and its own antigenic specificity appears to be partly related to the Fc fragment of IgA and to Fab fragments of known immunoglobulins, but its net charge is negative at pH 8.8. Its molecule seems to possess kappa but not lambda light polypeptide chains. Implications of this discovery are discussed.</p>
PY - 1977
SP - 24
EP - 7
T2 - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association
TI - Preliminary investigations on abnormal immunoglobulin(s) in leprosy.
VL - 45
SN - 0148-916X
ER -