TY - JOUR KW - Adolescent KW - African Americans KW - African Continental Ancestry Group KW - Bone Cysts KW - Diagnosis, Differential KW - Fingers KW - Granuloma KW - Humans KW - leprosy KW - Middle Aged KW - Sarcoidosis KW - South Africa KW - Tuberculosis AU - Leibowitz M R AU - Essop A R AU - Schamroth C L AU - Blumsohn D AU - Smith E H AB -

Six black South Africans with sarcoid dactylitis are described. By the term sarcoid dactylitis we mean sarcoid involvement of the bone and soft tissue of the fingers. Three of the six patients developed dactylitis during the course of chronic sarcoid. These patients had multisystem disease. In all three patients dactylitis developed after the diagnosis of sarcoid was established. However, in the other three patients dactylitis was the presenting feature of sarcoidosis, and none of these patients had evidence of chronic fibrotic sarcoid elsewhere. This finding is at variance with the observation that bony sarcoid is always a feature of chronic, poor prognosis, fibrotic sarcoid of all organ systems; these patients may form a sub-group with bony involvement and good prognosis. The significance, however, of this latter localized presentation of sarcoid is that clinically and histologically it is easily confused with tuberculoid leprosy and has been misdiagnosed.

BT - Seminars in arthritis and rheumatism C1 - http://www.ncbi.nlm.nih.gov/pubmed/4081788?dopt=Abstract DA - 1985 May DO - 10.1016/0049-0172(85)90042-3 IS - 4 J2 - Semin. Arthritis Rheum. LA - eng N2 -

Six black South Africans with sarcoid dactylitis are described. By the term sarcoid dactylitis we mean sarcoid involvement of the bone and soft tissue of the fingers. Three of the six patients developed dactylitis during the course of chronic sarcoid. These patients had multisystem disease. In all three patients dactylitis developed after the diagnosis of sarcoid was established. However, in the other three patients dactylitis was the presenting feature of sarcoidosis, and none of these patients had evidence of chronic fibrotic sarcoid elsewhere. This finding is at variance with the observation that bony sarcoid is always a feature of chronic, poor prognosis, fibrotic sarcoid of all organ systems; these patients may form a sub-group with bony involvement and good prognosis. The significance, however, of this latter localized presentation of sarcoid is that clinically and histologically it is easily confused with tuberculoid leprosy and has been misdiagnosed.

PY - 1985 SP - 232 EP - 7 T2 - Seminars in arthritis and rheumatism TI - Sarcoid dactylitis in black South African patients. VL - 14 SN - 0049-0172 ER -