TY - JOUR
KW - Adult
KW - Aged
KW - Australia
KW - Child
KW - Child, Preschool
KW - Female
KW - Humans
KW - Inflammation
KW - Male
KW - Microscopy, Electron
KW - Middle Aged
KW - Mycobacterium Infections
KW - Mycobacterium Infections, Nontuberculous
KW - Necrosis
KW - Nontuberculous Mycobacteria
KW - Recurrence
KW - Skin
KW - Skin Diseases, Infectious
KW - Skin Ulcer
AU - Hayman J
AU - McQueen A
AB - <p>The pathology of cutaneous ulcers resulting from Mycobacterium ulcerans infection is reviewed. Initial infection causes ulceration with necrosis of the dermis and a septate panniculitis in subcutaneous fat. There is little cellular reaction despite the presence of large numbers of organisms. Recurrent or persistent infection produces a granulomatous reaction with epithelioid macrophages, variable numbers of giant cells of the Langhans type, and relatively few organisms. This type of reaction is associated with more successful treatment of the disease and appears analogous to the tuberculoid form of leprosy.</p>
BT - Pathology
C1 - http://www.ncbi.nlm.nih.gov/pubmed/4094789?dopt=Abstract
DA - 1985 Oct
DO - 10.3109/00313028509084759
IS - 4
J2 - Pathology
LA - eng
N2 - <p>The pathology of cutaneous ulcers resulting from Mycobacterium ulcerans infection is reviewed. Initial infection causes ulceration with necrosis of the dermis and a septate panniculitis in subcutaneous fat. There is little cellular reaction despite the presence of large numbers of organisms. Recurrent or persistent infection produces a granulomatous reaction with epithelioid macrophages, variable numbers of giant cells of the Langhans type, and relatively few organisms. This type of reaction is associated with more successful treatment of the disease and appears analogous to the tuberculoid form of leprosy.</p>
PY - 1985
SP - 594
EP - 600
T2 - Pathology
TI - The pathology of Mycobacterium ulcerans infection.
VL - 17
SN - 0031-3025
ER -