TY - JOUR KW - Adolescent KW - Adult KW - Animals KW - Dapsone KW - Drug Resistance, Microbial KW - Foot KW - Humans KW - leprosy KW - Mice KW - Mycobacterium leprae AU - Vaishnavi C AU - Ganguly N K AU - Kumar B AU - Kaur S AU - Chakravarti R N AB -

20 carefully selected untreated patients of bacilliferous leprosy were investigated for primary dapsone resistance by foot pad inoculation. Mice were fed on 0.001 g% and 0.01 g% of dapsone during the period of study. Mice in the control group were given normal rodent feed only. Animals were sacrificed from 6 month onwards at 6 week intervals upto 9 months. In two animals the growth of M. leprae was not inhibited by 0.001 g% concentration of dapsone in diet, but was completely inhibited by 0.01 g% of dapsone.

BT - Indian journal of leprosy C1 - http://www.ncbi.nlm.nih.gov/pubmed/3913705?dopt=Abstract CN - Infolep Library - available DA - 1985 Jul-Sep IS - 3 J2 - Indian J Lepr LA - eng N2 -

20 carefully selected untreated patients of bacilliferous leprosy were investigated for primary dapsone resistance by foot pad inoculation. Mice were fed on 0.001 g% and 0.01 g% of dapsone during the period of study. Mice in the control group were given normal rodent feed only. Animals were sacrificed from 6 month onwards at 6 week intervals upto 9 months. In two animals the growth of M. leprae was not inhibited by 0.001 g% concentration of dapsone in diet, but was completely inhibited by 0.01 g% of dapsone.

PY - 1985 SP - 507 EP - 13 T2 - Indian journal of leprosy TI - Primary dapsone resistance in leprosy. VL - 57 SN - 0254-9395 ER -