Three experiments, using different routes and doses of infection, were conducted using 42 armadillos. Thirty-six of them developed generalized disease. There is no significant sex or age difference in susceptibility. Route and dose of infection make very little difference in the disease prevalence except that the intravenous administration of a large dose reduces the period of development of generalized disease. It is quite possible that in armadillos the resistance to the disease is partly genetic. Although a majority of the armadillos developed lepromatous disease, borderline leproma is fairly common. In skin nodules large colonies of extracellular bacilli are demonstrated. Bacilli are also demonstrated in liver parenchymal cells.
BT - The American journal of tropical medicine and hygiene C1 - http://www.ncbi.nlm.nih.gov/pubmed/3882008?dopt=Abstract DA - 1985 Jan DO - 10.4269/ajtmh.1985.34.151 IS - 1 J2 - Am. J. Trop. Med. Hyg. LA - eng N2 -Three experiments, using different routes and doses of infection, were conducted using 42 armadillos. Thirty-six of them developed generalized disease. There is no significant sex or age difference in susceptibility. Route and dose of infection make very little difference in the disease prevalence except that the intravenous administration of a large dose reduces the period of development of generalized disease. It is quite possible that in armadillos the resistance to the disease is partly genetic. Although a majority of the armadillos developed lepromatous disease, borderline leproma is fairly common. In skin nodules large colonies of extracellular bacilli are demonstrated. Bacilli are also demonstrated in liver parenchymal cells.
PY - 1985 SP - 151 EP - 61 T2 - The American journal of tropical medicine and hygiene TI - Manifestations of experimental leprosy in the armadillo. VL - 34 SN - 0002-9637 ER -