TY - JOUR
KW - Animals
KW - Dapsone
KW - Drug Evaluation, Preclinical
KW - leprosy
KW - Rabbits
AU - Kulkarni V M
AU - Mishra D S
AB - <p>Several prodrugs of dapsone have been prepared and evaluated in vivo for the release of parent drug. The prodrug: 4,4'-dibutyrylaminodiphenyl sulfone gave blood levels above 0.5 micrograms/ml of DDS for about 34 days in rabbits injected intragluteally. The results have been compared with DDS and DADDS.</p>
BT - Indian journal of leprosy
C1 - http://www.ncbi.nlm.nih.gov/pubmed/3835207?dopt=Abstract
CN - Infolep Library - available
DA - 1985 Oct-Dec
IS - 4
J2 - Indian J Lepr
LA - eng
N2 - <p>Several prodrugs of dapsone have been prepared and evaluated in vivo for the release of parent drug. The prodrug: 4,4'-dibutyrylaminodiphenyl sulfone gave blood levels above 0.5 micrograms/ml of DDS for about 34 days in rabbits injected intragluteally. The results have been compared with DDS and DADDS.</p>
PY - 1985
SP - 756
EP - 62
T2 - Indian journal of leprosy
TI - Chemical drug delivery systems: I. Preparation and evaluation of prodrugs of dapsone.
VL - 57
SN - 0254-9395
ER -