TY - JOUR KW - Acute Kidney Injury KW - Adult KW - Dapsone KW - Drug Hypersensitivity KW - Drug Therapy, Combination KW - Humans KW - leprosy KW - Male KW - Nephritis, Interstitial KW - Rifampin AU - Dedhia N M AU - Almeida A F AU - Khanna U B AU - Mittal B V AU - Acharya V M AB -

A leprosy patient who developed acute renal failure on multidrug therapy is reported. The patient had initially received a once-weekly dose of rifampin and after he had stopped taking the drug for a time, was given rifampin on a once-monthly dose schedule. He recovered completely from his acute renal failure. Kidney biopsy showed interstitial nephritis with mononuclear and eosinophilic cellular infiltrates.

BT - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association C1 - http://www.ncbi.nlm.nih.gov/pubmed/3746041?dopt=Abstract DA - 1986 Sep IS - 3 J2 - Int. J. Lepr. Other Mycobact. Dis. LA - eng N2 -

A leprosy patient who developed acute renal failure on multidrug therapy is reported. The patient had initially received a once-weekly dose of rifampin and after he had stopped taking the drug for a time, was given rifampin on a once-monthly dose schedule. He recovered completely from his acute renal failure. Kidney biopsy showed interstitial nephritis with mononuclear and eosinophilic cellular infiltrates.

PY - 1986 SP - 380 EP - 2 T2 - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association TI - Acute renal failure--a complication of new multidrug regimen for treatment of leprosy. VL - 54 SN - 0148-916X ER -