56 lepromatous leprosy patients with an initial average BI of 4.45 were administered once a month 600 mg of Rifampicin, 100 mg of Clofazimine on alternate days and 100 mg of Dapsone daily. None of these patients became smear negative in 2 years, and the same regimen was continued further. Two patients have become negative in 3 years and treatment has been stopped in them. The study indicates that highly bacilliferous LL/BL patients are likely to need 3 years or more of MDT for achieving bacterial negativity.
BT - Indian journal of leprosy C1 - http://www.ncbi.nlm.nih.gov/pubmed/3611859?dopt=Abstract CN - Infolep Library - available DA - 1987 Jan-Mar IS - 1 J2 - Indian J Lepr LA - eng N2 -56 lepromatous leprosy patients with an initial average BI of 4.45 were administered once a month 600 mg of Rifampicin, 100 mg of Clofazimine on alternate days and 100 mg of Dapsone daily. None of these patients became smear negative in 2 years, and the same regimen was continued further. Two patients have become negative in 3 years and treatment has been stopped in them. The study indicates that highly bacilliferous LL/BL patients are likely to need 3 years or more of MDT for achieving bacterial negativity.
PY - 1987 SP - 36 EP - 43 T2 - Indian journal of leprosy TI - Follow up of BL/LL patients on a slightly modified WHO regimen of multidrug therapy. VL - 59 SN - 0254-9395 ER -