TY - JOUR KW - Adult KW - Animals KW - Clofazimine KW - Dapsone KW - Drug Resistance, Microbial KW - Humans KW - leprosy KW - Male KW - Mice KW - Mycobacterium leprae AU - Kar H K AU - Bhatia V N AU - Harikrishnan S AB -

A preliminary report is presented on the finding in a patient with lepromatous leprosy relapsing after maintaining clinical inactivity and bacterial negativity with dapsone monotherapy for a period of 23 years. Interestingly, Mycobacterium leprae from the fresh skin lesions revealed resistance to both clofazimine and dapsone by standard mouse foot pad testing.

BT - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association C1 - http://www.ncbi.nlm.nih.gov/pubmed/3528345?dopt=Abstract DA - 1986 Sep IS - 3 J2 - Int. J. Lepr. Other Mycobact. Dis. LA - eng N2 -

A preliminary report is presented on the finding in a patient with lepromatous leprosy relapsing after maintaining clinical inactivity and bacterial negativity with dapsone monotherapy for a period of 23 years. Interestingly, Mycobacterium leprae from the fresh skin lesions revealed resistance to both clofazimine and dapsone by standard mouse foot pad testing.

PY - 1986 SP - 389 EP - 91 T2 - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association TI - Combined clofazimine- and dapsone-resistant leprosy. A case report. VL - 54 SN - 0148-916X ER -