27 histologically confirmed indeterminate leprosy cases were evaluated clinically and histopathologically at the SLR & TC, Karigiri, South India in 1985. The main clinical finding was a single or multiple (up to 3) patches. This was found in 25 (92%) of 27 cases. 2 cases only showed an area of anaesthesia without any skin lesion. Loss of sensation was present in 22 cases (81%). Histologically all cases (100%) showed lymphohistiocytic infiltration around the dermal structures and around/in the dermal nerves. AF bacilli were found in 17 cases (63%). They were detected most commonly in cellular infiltrate in the dermis (7 cases, 26%) and secondly in the dermal nerves (5 cases, 14%). Careful search and deeper sections increased the chance of detecting bacilli. Criteria for histological diagnosis were also discussed.
BT - Indian journal of leprosy C1 - http://www.ncbi.nlm.nih.gov/pubmed/3451924?dopt=Abstract CN - Infolep Library - available DA - 1987 Oct-Dec IS - 4 J2 - Indian J Lepr LA - eng N2 -27 histologically confirmed indeterminate leprosy cases were evaluated clinically and histopathologically at the SLR & TC, Karigiri, South India in 1985. The main clinical finding was a single or multiple (up to 3) patches. This was found in 25 (92%) of 27 cases. 2 cases only showed an area of anaesthesia without any skin lesion. Loss of sensation was present in 22 cases (81%). Histologically all cases (100%) showed lymphohistiocytic infiltration around the dermal structures and around/in the dermal nerves. AF bacilli were found in 17 cases (63%). They were detected most commonly in cellular infiltrate in the dermis (7 cases, 26%) and secondly in the dermal nerves (5 cases, 14%). Careful search and deeper sections increased the chance of detecting bacilli. Criteria for histological diagnosis were also discussed.
PY - 1987 SP - 399 EP - 404 T2 - Indian journal of leprosy TI - Indeterminate leprosy: a clinical and histopathological evaluation. VL - 59 SN - 0254-9395 ER -