TY - JOUR
KW - Adult
KW - Aspirin
KW - Chloramphenicol
KW - Dapsone
KW - Drug Interactions
KW - Female
KW - Half-Life
KW - Humans
KW - leprosy
KW - Male
KW - Middle Aged
AU - Garg S K
AU - Kumar B
AU - Shukla V K
AU - Bakaya V
AU - Lal R
AU - Kaur S
AB - <p>Pharmacokinetics of aspirin and chloramphenicol was studied in 16 normal and 16 patients suffering from leprosy. A significant increase (p less than 0.05) in the elimination half-life of chloramphenicol was observed before and after dapsone treatment in leprotic patients as compared with the normal volunteers, while no significant difference was observed in any of the pharmacokinetic parameters with aspirin.</p>
BT - International journal of clinical pharmacology, therapy, and toxicology
C1 - http://www.ncbi.nlm.nih.gov/pubmed/3403099?dopt=Abstract
DA - 1988 Apr
IS - 4
J2 - Int J Clin Pharmacol Ther Toxicol
LA - eng
N2 - <p>Pharmacokinetics of aspirin and chloramphenicol was studied in 16 normal and 16 patients suffering from leprosy. A significant increase (p less than 0.05) in the elimination half-life of chloramphenicol was observed before and after dapsone treatment in leprotic patients as compared with the normal volunteers, while no significant difference was observed in any of the pharmacokinetic parameters with aspirin.</p>
PY - 1988
SP - 204
EP - 5
T2 - International journal of clinical pharmacology, therapy, and toxicology
TI - Pharmacokinetics of aspirin and chloramphenicol in normal and leprotic patients before and after dapsone therapy.
VL - 26
SN - 0174-4879
ER -