TY - JOUR KW - Antigens, Bacterial KW - Enzyme-Linked Immunosorbent Assay KW - Glycolipids KW - Humans KW - Immunoglobulin M KW - leprosy KW - Longitudinal studies KW - Mycobacterium leprae KW - Papua New Guinea KW - Prospective Studies KW - Rural Population AU - Baumgart K AU - Britton W AU - Basten A AU - Bagshawe A AB -

This study reports on the usefulness of an IgM phenolic glycolipid 1 (PGL-1) ELISA for serodiagnosis of leprosy in the first year of a prospective longitudinal community survey in a high (8.8%) prevalence village in Papua New Guinea. The IgM PGL-1 ELISA had limited value as a screening method for detection of new cases. Many normal persons, particularly children, had elevated IgM anti-PGL-1 antibodies, presumably a consequence of early subclinical infection.

BT - Transactions of the Royal Society of Tropical Medicine and Hygiene C1 - http://www.ncbi.nlm.nih.gov/pubmed/3332501?dopt=Abstract DA - 1987 DO - 10.1016/0035-9203(87)90388-9 IS - 6 J2 - Trans. R. Soc. Trop. Med. Hyg. LA - eng N2 -

This study reports on the usefulness of an IgM phenolic glycolipid 1 (PGL-1) ELISA for serodiagnosis of leprosy in the first year of a prospective longitudinal community survey in a high (8.8%) prevalence village in Papua New Guinea. The IgM PGL-1 ELISA had limited value as a screening method for detection of new cases. Many normal persons, particularly children, had elevated IgM anti-PGL-1 antibodies, presumably a consequence of early subclinical infection.

PY - 1987 SP - 1030 EP - 2 T2 - Transactions of the Royal Society of Tropical Medicine and Hygiene TI - Use of phenolic glycolipid 1 for serodiagnosis of leprosy in a high prevalence village in Papua New Guinea. VL - 81 SN - 0035-9203 ER -