TY - JOUR KW - Animals KW - Anti-Bacterial Agents KW - Cefoxitin KW - Cefuroxime KW - Cephalosporins KW - Female KW - leprosy KW - Mezlocillin KW - Mice KW - Mycobacterium leprae KW - Penicillins AU - Shepard C C AU - Van Landingham R M AU - Walker L L AU - Good R C AB -
Twelve beta-lactam antibiotics were tested for activity against Mycobacterium leprae growing in the foot pads of mice. Two cephalosporins (7-aminocephalosporanic acid and cefuroxime) and one cephamycin (cefoxitin) showed significant activity against M. leprae, and one penicillin (mezlocillin) exerted possible growth-promoting activity. These results suggest that particular molecular structures may be required for activity against M. leprae.
BT - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association C1 - http://www.ncbi.nlm.nih.gov/pubmed/3298478?dopt=Abstract DA - 1987 Jun IS - 2 J2 - Int. J. Lepr. Other Mycobact. Dis. LA - eng N2 -Twelve beta-lactam antibiotics were tested for activity against Mycobacterium leprae growing in the foot pads of mice. Two cephalosporins (7-aminocephalosporanic acid and cefuroxime) and one cephamycin (cefoxitin) showed significant activity against M. leprae, and one penicillin (mezlocillin) exerted possible growth-promoting activity. These results suggest that particular molecular structures may be required for activity against M. leprae.
PY - 1987 SP - 322 EP - 7 T2 - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association TI - Activity of selected beta-lactam antibiotics against Mycobacterium leprae. VL - 55 SN - 0148-916X ER -