TY - JOUR KW - Adult KW - Clofazimine KW - Dapsone KW - Drug Resistance, Microbial KW - Drug Therapy, Combination KW - Female KW - Humans KW - leprosy KW - Male KW - Rifampin AU - Tiwari V D AU - Tutakne M A AU - Singh G AU - Dutta R K AB -
Fifty eight cases including 44 paucibacillary and 14 multibacillary leprosy diagnosed at Command Hospital SC Pune were hospitalised for the entire period of multidrug therapy. 76% cases belonged to high endemic states of India. Reactions occurred in 13 cases during treatment, type I in 10 and type II in three. 7 Multibacillary cases experienced reaction. 69% reaction patients developed reaction within two months of starting MDT and all of them were multibacillary. Usually it took 3-6 months for majority (61.5%) of reactions subside completely. In 65.5% paucibacillary patients activity subsided within twelve months, however 70.5% paucibacillary cases took more than six months to exhibit subsidence of activity. In 13 multibacillary cases activity subsided by 18 months though bacteriological negativity was obtained from fourth to twelve months.
BT - Indian journal of leprosy C1 - http://www.ncbi.nlm.nih.gov/pubmed/3204277?dopt=Abstract CN - Infolep Library - available DA - 1988 Jan IS - 1 J2 - Indian J Lepr LA - eng N2 -Fifty eight cases including 44 paucibacillary and 14 multibacillary leprosy diagnosed at Command Hospital SC Pune were hospitalised for the entire period of multidrug therapy. 76% cases belonged to high endemic states of India. Reactions occurred in 13 cases during treatment, type I in 10 and type II in three. 7 Multibacillary cases experienced reaction. 69% reaction patients developed reaction within two months of starting MDT and all of them were multibacillary. Usually it took 3-6 months for majority (61.5%) of reactions subside completely. In 65.5% paucibacillary patients activity subsided within twelve months, however 70.5% paucibacillary cases took more than six months to exhibit subsidence of activity. In 13 multibacillary cases activity subsided by 18 months though bacteriological negativity was obtained from fourth to twelve months.
PY - 1988 SP - 71 EP - 6 T2 - Indian journal of leprosy TI - Multidrug therapy in hospitalised leprosy cases. VL - 60 SN - 0254-9395 ER -