TY - JOUR
KW - Adjuvants, Immunologic
KW - Cells, Cultured
KW - Humans
KW - Interferon-gamma
KW - leprosy
KW - Peptide Fragments
KW - T-Lymphocytes
KW - Thymopentin
KW - Thymopoietins
KW - Thymus Hormones
AU - Munno I
AU - Pellegrino N M
AU - Fumo G
AU - BARBIERI G
AU - Polimeno G
AU - Filippis V
AU - Jirillo E
AB - <p>Twenty three patients with lepromatous leprosy (LL) not in reactional phase and bacteriologically negative were evaluated for their immune status (T cell frequency and interferon gamma production). In six patients with deficits of both immune parameters, a synthetic thymic extract (TP-5) was administered. At the end of the treatment, a full recovery of immune dysfunction was observed. In the light of these results, the efficacy of TP-5 as an immunomodulating agent in LL patients is discussed.</p>
BT - Cytobios
C1 - http://www.ncbi.nlm.nih.gov/pubmed/3123147?dopt=Abstract
DA - 1987
IS - 210-211
J2 - Cytobios
LA - eng
N2 - <p>Twenty three patients with lepromatous leprosy (LL) not in reactional phase and bacteriologically negative were evaluated for their immune status (T cell frequency and interferon gamma production). In six patients with deficits of both immune parameters, a synthetic thymic extract (TP-5) was administered. At the end of the treatment, a full recovery of immune dysfunction was observed. In the light of these results, the efficacy of TP-5 as an immunomodulating agent in LL patients is discussed.</p>
PY - 1987
SP - 167
EP - 73
T2 - Cytobios
TI - Effects of a synthetic extract (thymopentin) on the immune system of lepromatous leprosy patients.
VL - 52
SN - 0011-4529
ER -