TY - JOUR
KW - coronavirus disease
KW - Hansen’s disease
KW - Leprosy Disease
KW - Leprosy reactions
AU - Hammad RRM
AU - Abdel-Alaeem HL
AU - Khalaf-Allah SM
AB - <p><strong>Background</strong></p>

<p>Coronavirus disease 2019 (COVID-19) is a serious worldwide health problem that affects direct and indirect however, the implications of COVID-19 co-infection in patients with Hansen’s disease remain uncertain this study aimed to assess the relationship between COVID-19 and leprosy and its reactions.</p>

<p><strong>Patients and methods</strong></p>

<p>This is a descriptive retrospective study conducted on 200 patients presented with different clinical forms of leprosy, according to COVID-19 infection, they divided into two groups, group I=98 COVID-19 positive patients and group II=102 COVID-19 negative patients.</p>

<p><strong>Results</strong></p>

<p>Significant decrease in COVID-19 co-infection among lepromatous leprosy patients with a significant decrease in leprosy reactions. Significant increase in COVID-19 co-infection among tuberculoid patients with a significant increase in leprosy reactions and in number of lepra bacilli detected by slit skin smear among COVID-19 negative patients ( P &lt;0.05). No significant difference between the two groups as regards the classification of leprosy, mode of infection of leprosy, and grade of disability ( P &gt;0.05).</p>

<p><strong>Conclusion</strong></p>

<p>COVID-19 co-infection may enhance leprosy reactions.</p>

BT - Al-Azhar Assiut Medical Journal
DA - 09/2026
DO - 10.4103/azmj.azmj_50_23
IS - 3
LA - ENG
M3 - Article 
N2 - <p><strong>Background</strong></p>

<p>Coronavirus disease 2019 (COVID-19) is a serious worldwide health problem that affects direct and indirect however, the implications of COVID-19 co-infection in patients with Hansen’s disease remain uncertain this study aimed to assess the relationship between COVID-19 and leprosy and its reactions.</p>

<p><strong>Patients and methods</strong></p>

<p>This is a descriptive retrospective study conducted on 200 patients presented with different clinical forms of leprosy, according to COVID-19 infection, they divided into two groups, group I=98 COVID-19 positive patients and group II=102 COVID-19 negative patients.</p>

<p><strong>Results</strong></p>

<p>Significant decrease in COVID-19 co-infection among lepromatous leprosy patients with a significant decrease in leprosy reactions. Significant increase in COVID-19 co-infection among tuberculoid patients with a significant increase in leprosy reactions and in number of lepra bacilli detected by slit skin smear among COVID-19 negative patients ( P &lt;0.05). No significant difference between the two groups as regards the classification of leprosy, mode of infection of leprosy, and grade of disability ( P &gt;0.05).</p>

<p><strong>Conclusion</strong></p>

<p>COVID-19 co-infection may enhance leprosy reactions.</p>

PB - Ovid Technologies (Wolters Kluwer Health)
PY - 2026
SP - 435 
EP -  439
T2 - Al-Azhar Assiut Medical Journal
TI - Leprosy disease and its reactions in the era of corona virus disease 2019
UR - https://www.ovid.com/jnls/aamj/pdf/10.4103/azmj.azmj_50_23~leprosy-disease-and-its-reactions-in-the-era-of-corona-virus
VL - 24
SN - 1687-1693, 2536-9652
ER -