Leprosy, recognized as one of the ancient diseases, predominantly affects the integumentary system and peripheral nerves. Nevertheless, central nervous system (CNS) involvement is a rare occurrence, with cortical manifestations being exceedingly infrequent. We present a case that aligns with this rarity, showcasing diffuse hyperintensities on magnetic resonance imaging (MRI) within the cortical region of the brain. The patient's clinical presentation was marked by seizures, necessitating targeted therapeutic interventions.
BT - The Journal of the Association of Physicians of India C1 - https://www.ncbi.nlm.nih.gov/pubmed/42543959 DA - 06/2026 DO - 10.59556/japi.74.1533 IS - 6S J2 - J Assoc Physicians India LA - ENG M3 - Article N2 -Leprosy, recognized as one of the ancient diseases, predominantly affects the integumentary system and peripheral nerves. Nevertheless, central nervous system (CNS) involvement is a rare occurrence, with cortical manifestations being exceedingly infrequent. We present a case that aligns with this rarity, showcasing diffuse hyperintensities on magnetic resonance imaging (MRI) within the cortical region of the brain. The patient's clinical presentation was marked by seizures, necessitating targeted therapeutic interventions.
PY - 2026 SP - 7 EP - 9 T2 - The Journal of the Association of Physicians of India TI - Seizures as Presenting Complaint of Cerebral Cortex Involvement in Leprosy VL - 74 SN - 0004-5772 ER -