TY - JOUR
KW - Dapsone
KW - Enzyme-Linked Immunosorbent Assay
KW - Hemagglutination Tests
KW - Humans
KW - leprosy
KW - Patient Compliance
KW - Sensitivity and Specificity
KW - Statistics as Topic
AU - Nagelkerke N J
AU - Fidler V
AU - Buwalda M
AB - <p>We explore the estimation of sensitivity and specificity of diagnostic tests when the true disease state is unknown. Instrumental variables which subdivide the patient population are used. A logistic model, relating these instrumental variables to the (unknown) true disease state is proposed. It is shown that this procedure allows the goodness-of-fit to the resulting model to be tested.</p>
BT - Statistics in medicine
C1 - http://www.ncbi.nlm.nih.gov/pubmed/3043622?dopt=Abstract
DA - 1988 Jul
DO - 10.1002/sim.4780070703
IS - 7
J2 - Stat Med
LA - eng
N2 - <p>We explore the estimation of sensitivity and specificity of diagnostic tests when the true disease state is unknown. Instrumental variables which subdivide the patient population are used. A logistic model, relating these instrumental variables to the (unknown) true disease state is proposed. It is shown that this procedure allows the goodness-of-fit to the resulting model to be tested.</p>
PY - 1988
SP - 739
EP - 44
T2 - Statistics in medicine
TI - Instrumental variables in the evaluation of diagnostic test procedures when the true disease state is unknown.
VL - 7
SN - 0277-6715
ER -