TY - JOUR KW - Animals KW - Antibodies, Bacterial KW - Antigens, Bacterial KW - Armadillos KW - Enzyme-Linked Immunosorbent Assay KW - Glycolipids KW - Immunoglobulin G KW - Immunoglobulin M KW - Kinetics KW - leprosy KW - Mycobacterium leprae AU - Vadiee A R AU - Shannon E J AU - Gillis T P AU - Mshana R N AU - Hastings R C AB -

The kinetics of antibody responses of Mycobacterium leprae-infected armadillos to phenolic glycolipid-I (PGL-I) were studied by means of ELISA. The levels of both IgG and IgM antibodies to PGL-I increased with time. Some animals were less susceptible to disseminations of M. leprae infection and lived longer than others. These animals had high absorbance values (greater than 0.7) for IgG anti-PGL-I compared to more susceptible armadillos that had lower absorbance values for IgG anti-PGL-I.

BT - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association C1 - http://www.ncbi.nlm.nih.gov/pubmed/3047283?dopt=Abstract DA - 1988 Sep IS - 3 J2 - Int. J. Lepr. Other Mycobact. Dis. LA - eng N2 -

The kinetics of antibody responses of Mycobacterium leprae-infected armadillos to phenolic glycolipid-I (PGL-I) were studied by means of ELISA. The levels of both IgG and IgM antibodies to PGL-I increased with time. Some animals were less susceptible to disseminations of M. leprae infection and lived longer than others. These animals had high absorbance values (greater than 0.7) for IgG anti-PGL-I compared to more susceptible armadillos that had lower absorbance values for IgG anti-PGL-I.

PY - 1988 SP - 422 EP - 7 T2 - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association TI - Armadillo IgG and IgM antibody responses to phenolic glycolipid-I during experimental infection with M. leprae. VL - 56 SN - 0148-916X ER -